687 Comparison of Perioperative Outcomes Betweenlaparoscopic Versus Open Versus Robotic Partialnephrectomy: A Systematic Review

Abstract Aim This systematic review aims to evaluate the perioperative outcomes between laparoscopic (LPN), open (OPN), and robotic-assisted partial nephrectomy (RPN) using standardised system, Clavien-Dindo Classification (CDC). Method The was conducted in accordance with PRISMA guidelines. A search performed on Cochrane, Embase PubMed databases. Articles January 2016 December 2021 were included. Perioperative investigated include: estimated blood loss (EBL), operating time (OT), conversion rate (CR), warm ischaemia (WIT), positive surgical margin (PSM), postoperative complications CDC. Results study included 12 studies, a total of 3,908 patients. (LPN = 1,120, OPN 1,206, RPN 1,580). LPN demonstrated lower overall EBL (p 0.004). There no significant difference OT 0.291), CR 0.200), WIT 0.760), PSM 0.549), CDC I 0.556), II 0.779) CDC≥III 0.663) three approaches. Conclusions Compared RPN, EBL. All other similar results treatment modalities. Future large-scale, prospective, randomised studies is necessary draw definitive conclusion from this analysis.